Intrinsic Connectivity Identifies the Hippocampus as a Main Crossroad between Alzheimer’s and Semantic Dementia-Targeted Networks

Intrinsic connectivity identifies the hippocampus as a main crossroad between Alzheimer ’ s and semantic dementia - targeted networks Running title : Brain networks , hippocampus and memory in dementia

Audrey Perrotin -selected Publications

1 La Joie, R., Landeau, B., Perrotin, A., Bejanin, A., Egret, S., Pelerin, A. et al. (2014). Intrinsic connectivity identifies the hippocampus as a main crossroad between Alzheimer's and semantic dementia-targeted networks. Neuron, 81, 1417-1428. Notes: Alzheimer's disease (AD) and semantic dementia (SD) are both characterized by severe atrophy in the hippocampus, a brain region underlying epis...

Progressively Disrupted Intrinsic Functional Connectivity of Basolateral Amygdala in Very Early Alzheimer’s Disease

Very early Alzheimer's disease (AD) - i.e., AD at stages of mild cognitive impairment (MCI) and mild dementia - is characterized by progressive structural and neuropathologic changes, such as atrophy or tangle deposition in medial temporal lobes, including hippocampus and entorhinal cortex and also adjacent amygdala. While progressively disrupted intrinsic connectivity of hippocampus with other...

Diverging Progression of Network Disruption and Atrophy in Alzheimer’s Disease and Semantic Dementia

The progression of cognitive deficits in Alzheimer's disease and semantic dementia is accompanied by grey matter atrophy and white matter deterioration. The impact of neuronal loss on the structural network connectivity in these dementia subtypes is, however, not well understood. In order to gain a more refined knowledge of the topological organization of white matter alterations in dementia, w...

ENERGY AWARE DISTRIBUTED PARTITIONING DETECTION AND CONNECTIVITY RESTORATION ALGORITHM IN WIRELESS SENSOR NETWORKS

 Mobile sensor networks rely heavily on inter-sensor connectivity for collection of data. Nodes in these networks monitor different regions of an area of interest and collectively present a global overview of some monitored activities or phenomena. A failure of a sensor leads to loss of connectivity and may cause partitioning of the network into disjoint segments. A number of approaches have be...